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Intermediate

Intermediate List


S. No. Product Name Intermediate Code CAS No. Chemical Name of Intermediates
1 Loratadine L5 31255-57-9 2-Cyano-3-(3-chlorophenethyl)pyridine
L7 31251-41-9 8-Chloro-10, 11-dihydro-4-aza-5H-dibenzo (a, d) cycloheptan-5-one
L8 38089-93-9 11-(N-Methyl-4-piperidinyl)-8-chloro-11-hydroxy- 6,11-dihydro-5H-benzo(5,6)cyclohepta (1,2-b) pyridine
LN8 119770-60-4 (1-Methyl-4-piperidinyl)[3-(2-3-chlorophenyl)ethyl-2-pyridinyl] methanone hydrochloride
L9 / LH9 38092-89-6 11-(N-Methyl-4-piperidinylidene)-8-chloro-6,11-dihydro-5H-benzo(5,6)cyclohepta (1,2-b) pyridine
2 Atorvastatin Calcium AT-8 125971-95-1 (4R-Cis)-1,1-Dimethylethyl-6-[2-[2-(4-Fluorophenyl)-5-(1-Isopropyl)-3-phenyl-4-[(Phenylamino)carbonyl]1H-pyrrol-1-yl]Ethyl]-2,2-Dimethyl-1,3-Dioxane-4-Acetate
3 Montelukast Sodium MTS05 152922-73-1 (1-mercaptomethyl) cyclopropane methyl acetate
MTN12 577953-88-9 [(R)-(E)]-1-[[[-1-[3-[2-(7-chloro-2-quinolinyl) ethenyl] phenyl] -3-[2-(1-hydroxy-1-methylethyl)phenyl] propyl]thio] methyl] Cyclopropane acetic acid dicyclohexylamine salt or
Montelukast Dicyclohexylamine Salt
4 Fexofenadine Hydrochloride D10 or FD3 154477-55-1 2-(4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-oxobutyl)phenyl)-2,2-dimethylacetic acid methyl ester
D12 83799-24-0 α,α-Dimethyl-4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl] Benzene acetic acid (Fexofenadine Base)
5 Rosuvastatin Calcium RT08 147118-37-4 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methyl sulfonyl) amino]pyrimidinyl-5-yl-carbaldehyde
RTN09 885477-83-8 N-[4-(4-fluorophenyl)-5-(bromo methyl)-6-(isopropyl pyrimidin-2-yl)-N-methyl methane sulfonamide triphenylphosphonium salt
RT10 289042-12-2 tert-butyl-2-((4R,6S)-6-((E)-2-(4(-(4-fluorophenyl)-6-isopropyl-2-(N-methyl methylsulphonamido)pyrimidin-5-yl) vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
RT11 355806-00-7 tert-Butyl-(6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl) amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoate
6 Sitagliptin Phosphate SG05 486460-23-5 (R)-tert-butyl(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazole[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluoro phenyl)butan-2-yl)carbamate
SG06/SGN06 486460-32-6 (R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4] triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl) butan-1-one
SG06M/SGN06M 1240038-86-1 (R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4] triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl) butan-1-one mandelate
SGN04 764667-65-4 (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4] triazolo [4,3-a] pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl) butan-2-one
SGN05 767340-03-4 (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4] triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl) but-2-en-2-amine
7 Olmesartan Medoxomil OL04 144690-92-6 (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl-5-(2-hydroxy propan-2-yl)-2-propyl-3-[[4-[2- (1-trityltetrazol-5-yl)phenyl] phenyl]methyl]imidazole-4-carboxylate
8 Saxagliptin Hydrochloride SX01 361442-01-5 N-Boc-3-hydroxy adamentyl glycine-L-cis-4,5-methanoprolinamide
SX04 709031-43-6 N-Boc-(S)-3-hydroxyadamentyl glycine -L-cis -4,5-methanoproline nitrile
SX05 945667-22-1 (S)-3-Hydroxyadamentyl glycine -L-cis -4,5-methano proline nitrile
9 Linagliptin LG02 853029-57-9 1-[(4-Methylquinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-bromoxanthine
LG03 668273-75-4 8-[(3R)-3-Boc-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione
10 Dapagliflozin Propanediol DP02 461432-24-6 Methyl-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]- D-Glucopyranoside
DP04 461432-25-7 (2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-[4-chloro-3-(4-ethoxybenzyl)phenyl]tetrahydro-2H-pyran-3,4,5-triyl triacetate
11 Canagliflozin Hemihydrate CG04 866607-35-4 (1S)-1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, 2,3,4,6-tetraacetate-D-Glucitol
12 Empagliflozin EG04 915095-99-7 (2S,3R,4R,5S,6R)-2-[4-chloro-3-[[4-[(3S)-oxolan-3-yl] oxyphenyl] methyl] phenyl]-6-(acetoxymethyl) oxane-3,4,5- triyl triacetate
S. No. Product Name Intermediate Code CAS No. Chemical Name of Intermediates
1A Loratadine L5 31255-57-9 2-Cyano-3-(3-chlorophenethyl)pyridine
1B Loratadine L7 31251-41-9 8-Chloro-10, 11-dihydro-4-aza-5H-dibenzo (a, d) cycloheptan-5-one
1C Loratadine L8 38089-93-9 11-(N-Methyl-4-piperidinyl)-8-chloro-11-hydroxy- 6,11-dihydro-5H-benzo(5,6)cyclohepta (1,2-b) pyridine
1D Loratadine LN8 119770-60-4 (1-Methyl-4-piperidinyl)[3-(2-3-chlorophenyl)ethyl-2-pyridinyl] methanone hydrochloride
1E Loratadine L9 / LH9 38092-89-6 11-(N-Methyl-4-piperidinylidene)-8-chloro-6,11-dihydro-5H-benzo(5,6)cyclohepta (1,2-b) pyridine
2 Atorvastatin Calcium AT-8 125971-95-1 (4R-Cis)-1,1-Dimethylethyl-6-[2-[2-(4-Fluorophenyl)-5-(1-Isopropyl)-3-phenyl-4-[(Phenylamino)carbonyl]1H-pyrrol-1-yl]Ethyl]-2,2-Dimethyl-1,3-Dioxane-4-Acetate
3A Montelukast Sodium MTS05 152922-73-1 (1-mercaptomethyl) cyclopropane methyl acetate
3B Montelukast Sodium MTN12 577953-88-9 [(R)-(E)] -1- [ [ [-1- [3-[2-(7-chloro-2-quinolinyl) ethenyl ] phenyl ] -3-[ 2-( 1-hydroxy -1- methylethyl ) phenyl ] propyl ]thio ] methyl ] Cyclopropane acetic acid dicyclohexylamine salt or Montelukast Dicyclohexylamine Salt
4A Fexofenadine Hydrochloride D10 or FD3 154477-55-1 2-(4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-oxobutyl)phenyl)-2,2-dimethylacetic acid methyl ester
4B Fexofenadine Hydrochloride D12 83799-24-0 α,α-Dimethyl-4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl] Benzene acetic acid (Fexofenadine Base)
5A Rosuvastatin Calcium RT08 147118-37-4 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methyl sulfonyl) amino]pyrimidinyl-5-yl-carbaldehyde
5B Rosuvastatin Calcium RTN09 885477-83-8 N-[4-( 4-fluorophenyl ) -5- ( bromo methyl ) -6- ( isopropyl pyrimidin-2-yl ) -N- methyl methane sulfonamide triphenylphosphonium salt
5C Rosuvastatin Calcium RT10 289042-12-2 tert - butyl-2- ( ( 4R,6S ) -6- ( (E)-2- ( 4 (- ( 4- fluorophenyl ) -6- isopropyl -2- ( N - methyl methylsulphonamido ) pyrimidin - 5 -yl ) vinyl )-2, 2-dimethyl - 1, 3-dioxan-4-yl )acetate
5D Rosuvastatin Calcium RT11 355806-00-7 tert-Butyl-(6E)-7- [4- ( 4 - fluorophenyl ) - 6 - isopropyl -2- [ methyl ( methylsulfonyl ) amino ] pyrimidin - 5 - yl ] - ( 3R, 5S ) -3, 5 - dihydroxyhept - 6 - enoate
6A Sitagliptin Phosphate SG05 486460-23-5 (R) - tert - butyl( 4-oxo-4- (3-( trifluoromethy l)-5, 6-dihydro-[1, 2, 4] triazole[4, 3-a] pyrazin-7 (8H)-yl ) -1- (2, 4, 5- trifluoro phenyl ) butan - 2 - yl ) carbamate
6B Sitagliptin Phosphate SG06/SGN06 486460-32-6 (R) - 3 - Amino - 1 -( 3 -( trifluoromethyl ) -5, 6 - dihydro - [1, 2, 4] triazolo [4, 3-a] pyrazin-7(8H)-yl ) -4- (2, 4, 5-trifluorophenyl ) butan-1-one
6C Sitagliptin Phosphate SG06M/SGN06M 1240038-86-1 (R) -3- amino-1- ( 3- ( trifluoromethyl ) -5, 6-dihydro- [1, 2, 4] triazolo [4, 3-a] pyrazin-7(8H)-yl ) -4- (2, 4, 5 - trifluorophenyl ) butan - 1 - one mandelate
6D Sitagliptin Phosphate SGN04 764667-65-4 (2Z)- 4 - Oxo - 4- [3 - ( trifluoromethyl )-5, 6 - dihydro - [1, 2, 4] triazolo [4, 3-a] pyrazine-7(8H)-yl ] -1- (2, 4, 5 - trifluorophenyl ) butan-2-one
6E Sitagliptin Phosphate SGN05 767340-03-4 (2Z) - 4 - Oxo - 4 - [ 3 - ( trifluoromethyl ) -5, 6 - dihydro [1, 2, 4] triazolo [4, 3-a] pyrazin- 7 (8H)-yl ] -1- (2, 4, 5 - trifluoropheny l) but - 2 - en - 2 - amine
7 Olmesartan Medoxomil OL04 144690-92-6 ( 5 - methyl - 2 - oxo - 1, 3 - dioxol - 4 - yl ) methyl -5- ( 2 - hydroxy propan - 2 - yl ) - 2 - propyl - 3 - [ [ 4 - [ 2 - ( 1 - trityltetrazol - 5 - yl ) phenyl ] phenyl ] methyl ] imidazole - 4 - carboxylate
8A Saxagliptin Hydrochloride SX01 361442-01-5 N - Boc - 3 - hydroxy adamentyl glycine - L - cis - 4 ,5 - methanoprolinamide
8B Saxagliptin Hydrochloride SX04 709031-43-6 N - Boc- (S)- 3 - hydroxyadamentyl glycine -L-cis -4, 5 - methanoproline nitrile
8C Saxagliptin Hydrochloride SX05 945667-22-1 (S)-3-Hydroxyadamentyl glycine -L- cis -4, 5-methano proline nitrile
9A Linagliptin LG02 853029-57-9 1-[ ( 4 - Methylquinazolin - 2 - yl ) methyl ] -3- methyl -7- ( 2- butyn- 1- yl ) -8- bromoxanthine
9B Linagliptin LG03 668273-75-4 8- [ (3R) - 3 - Boc - aminopiperidin -1- yl ] -7- ( but-2-yn-1-yl ) -3-methyl-1- [ ( 4 - methylquinazolin - 2 - yl ) methyl ] -3, 7 - dihydro - 1H - purine - 2, 6 - dione
10A Dapagliflozin Propanediol DP02 461432-24-6 Methyl-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]- D-Glucopyranoside
10B Dapagliflozin Propanediol DP04 461432-25-7 (2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-[4-chloro-3-(4-ethoxybenzyl)phenyl]tetrahydro-2H-pyran-3,4,5-triyl triacetate
11A Canagliflozin Hemihydrate CG04 866607-35-4 (1S)-1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, 2,3,4,6-tetraacetate-D-Glucitol
12A Empagliflozin EG04 915095-99-7 (2S,3R,4R,5S,6R)-2-[4-chloro-3-[[4-[(3S)-oxolan-3-yl] oxyphenyl] methyl] phenyl]-6-(acetoxymethyl) oxane-3,4,5- triyl triacetate

Note: The above intermediates are not for sales where the Patents are applicable & still valid.